Chemotherapy Research Today is a free monthly online journal that collates and summarizes the latest research about Chemotherapy, including details on cancer treatment, side effects, drugs.
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Volume 6 (2009), Issue 6 (June)
- Targeting innate immunity protein kinase signalling in inflammation.
Nat Rev Drug Discov, 8(6): 480-99. [Abstract] [Full-text]
- Parental misinterpretations of over-the-counter pediatric cough and cold medication labels.
Pediatrics, 123(6): 1464-71. [Abstract] [Full-text]
- Dose-finding study of weekly docetaxel, epirubicin and capecitabine, as first-line treatment in advanced breast cancer.
Cancer Chemother Pharmacol, 64(2): 407-12. [Abstract] [Full-text]
- Antibiotic prophylaxis for the prevention of infection after major limb amputation.
Eur J Vasc Endovasc Surg, 37(6): 696-703. [Abstract] [Full-text]
- Low-molecular-weight dendrons for DNA binding and release by reduction-triggered degradation of multivalent interactions.
Chemistry, 15(23): 5656-60. [Abstract] [Full-text]
- Encapsulation and sustained release of curcumin using superparamagnetic silica reservoirs.
Chemistry, 15(23): 5661-5. [Abstract] [Full-text]
- Further improvement in outcomes of nasopharyngeal carcinoma with optimized radiotherapy and induction plus concomitant chemotherapy: an update of the Milan experience.
Int J Radiat Oncol Biol Phys, 74(3): 774-80. [Abstract] [Full-text]
- A phase II study of gemcitabine in combination with oxaliplatin as first-line chemotherapy in patients with inoperable biliary tract cancer.
Cancer Chemother Pharmacol, 64(2): 371-7. [Abstract] [Full-text]
- A phase II randomized trial of gemcitabine-docetaxel versus gemcitabine-cisplatin in patients with advanced non-small cell lung carcinoma.
Cancer Chemother Pharmacol, 64(2): 379-84. [Abstract] [Full-text]
- Fixed-dose rate infusion of gemcitabine and weekly cisplatin in elderly or poor performance status patients with unresectable non-small cell lung cancer.
Cancer Chemother Pharmacol, 64(2): 385-90. [Abstract] [Full-text]
- Non-pegylated liposomal doxorubicin and docetaxel in metastatic breast cancer: final results of a phase II trial.
Cancer Chemother Pharmacol, 64(2): 401-6. [Abstract] [Full-text]
- Phase II study of capecitabine and trastuzumab combination chemotherapy in patients with HER2 overexpressing metastatic breast cancers resistant to both anthracyclines and taxanes.
Cancer Chemother Pharmacol, 64(2): 361-9. [Abstract] [Full-text]
- A phase I/II trial of docetaxel and oxaliplatin in patients with advanced gastric cancer.
Cancer Chemother Pharmacol, 64(2): 347-53. [Abstract] [Full-text]
- TP53 codon 72 polymorphism associated with prognosis in patients with advanced gastric cancer treated with paclitaxel and cisplatin.
Cancer Chemother Pharmacol, 64(2): 355-60. [Abstract] [Full-text]
- Phase II evaluation of nedaplatin and paclitaxel in patients with metastatic esophageal carcinoma.
Cancer Chemother Pharmacol, 64(2): 327-33. [Abstract] [Full-text]
- Simplified FOLFIRI in pre-treated patients with metastatic gastric cancer.
Cancer Chemother Pharmacol, 64(2): 301-6. [Abstract] [Full-text]
- Gemcitabine and oxaliplatin combination as first-line treatment for advanced pancreatic cancer: a multicenter phase II study.
Cancer Chemother Pharmacol, 64(2): 317-25. [Abstract] [Full-text]
- Pharmacokinetic evaluation of platinum derived from cisplatin administered alone and with pemetrexed in head and neck cancer patients.
Cancer Chemother Pharmacol, 64(2): 233-41. [Abstract] [Full-text]
- Changes of host immunity in relation to efficacy in liver cirrhosis patients with advanced hepatocellular carcinoma treated by intra-arterial chemotherapy.
Cancer Chemother Pharmacol, 64(2): 271-7. [Abstract] [Full-text]
- Photodynamic therapy (PDT): a short review on cellular mechanisms and cancer research applications for PDT.
J Photochem Photobiol B, 96(1): 1-8. [Abstract] [Full-text]
- Histone deacetylase inhibitor induced modulation of anti-estrogen therapy.
Cancer Lett, 280(2): 184-91. [Abstract] [Full-text]
- Safety and efficacy of isolated limb infusion with cytotoxic drugs in elderly patients with advanced locoregional melanoma.
Ann Surg, 249(6): 1008-13. [Abstract] [Full-text]
- Randomized, double-blind, placebo-controlled study of paliperidone extended-release and quetiapine in inpatients with recently exacerbated schizophrenia.
Am J Psychiatry, 166(6): 691-701. [Abstract] [Full-text]
- Measuring the quality of medication use in older adults.
J Am Geriatr Soc, 57(6): 1096-102. [Abstract] [Full-text]
- Potentially inappropriate medications and functional decline in elderly hospitalized patients.
J Am Geriatr Soc, 57(6): 1007-14. [Abstract] [Full-text]
- Comparative chlorpyrifos pharmacokinetics via multiple routes of exposure and vehicles of administration in the adult rat.
Toxicology, 261(1): 47-58. [Abstract] [Full-text]
- Flexible polymerosomes--an alternative vehicle for topical delivery.
Colloids Surf B Biointerfaces, 72(1): 161-6. [Abstract] [Full-text]
- A randomized double-blind trial of the effects of hormone therapy on delayed verbal recall in older women.
Psychoneuroendocrinology, 34(7): 1065-74. [Abstract] [Full-text]
- Facial paralysis after superselective intra-arterial chemotherapy via the middle meningeal artery in maxillary cancer.
Auris Nasus Larynx, 36(4): 479-81. [Abstract] [Full-text]
- Chitosan-chondroitin sulfate based matrix tablets for colon specific delivery of indomethacin.
AAPS PharmSciTech, 10(2): 670-7. [Abstract] [Full-text]
- Conjugated oral versus transdermal estrogen replacement in girls with Turner syndrome: a pilot comparative study.
J Clin Endocrinol Metab, 94(6): 2009-14. [Abstract] [Full-text]
- Bone mineral density, growth, and thyroid function in long-term survivors of pediatric Hodgkin's lymphoma treated with chemotherapy only.
J Clin Endocrinol Metab, 94(6): 1904-9. [Abstract] [Full-text]
- A modular diffusion barrier based on phase separation for localized delivery of discrete drug volumes in aqueous environments.
Lab Chip, 9(12): 1801-5. [Abstract] [Full-text]
- A phase II trial of preoperative chemotherapy with epirubicin, cisplatin and capecitabine for patients with localised gastro-oesophageal junctional adenocarcinoma.
Br J Cancer, 100(11): 1725-30. [Abstract] [Full-text]
- A multicenter phase II study of the combination of oxaliplatin, irinotecan and capecitabine in the first-line treatment of metastatic colorectal cancer.
Br J Cancer, 100(11): 1720-4. [Abstract] [Full-text]
- Practice patterns of intraperitoneal chemotherapy in women with ovarian cancer.
Gynecol Oncol, 114(1): 37-41. [Abstract] [Full-text]
- Case report: Recurrence of a uterine tumor resembling ovarian sex-cord tumor.
Gynecol Oncol, 114(1): 140-2. [Abstract] [Full-text]
- Adjuvant carboplatin and paclitaxel chemotherapy interposed with involved field radiation for advanced endometrial cancer.
Gynecol Oncol, 114(1): 94-8. [Abstract] [Full-text]
- Intraperitoneal access via direct puncture is an alternative way to deliver intraperitoneal chemotherapy in ovarian, fallopian tube and primary peritoneal cancer.
Gynecol Oncol, 114(1): 42-7. [Abstract] [Full-text]
- Self-assembly of pH-responsive fluorinated dendrimer-based particulates for drug delivery and noninvasive imaging.
Biomaterials, 30(23): 3946-55. [Abstract] [Full-text]
- In-vitro osteogenesis of synovium stem cells induced by controlled release of bisphosphate additives from microspherical mesoporous silica composite.
Biomaterials, 30(23): 3996-4005. [Abstract] [Full-text]
- Masking and triggered unmasking of targeting ligands on nanocarriers to improve drug delivery to brain tumors.
Biomaterials, 30(23): 3986-95. [Abstract] [Full-text]
- Direct formation of proteo-liposomes by in vitro synthesis and cellular cytosolic delivery with connexin-expressing liposomes.
Biomaterials, 30(23): 3971-7. [Abstract] [Full-text]
- In vivo evaluation of vaginal films for mucosal delivery of nitric oxide.
Biomaterials, 30(23): 3978-85. [Abstract] [Full-text]
- Mixed micelle systems formed from critical micelle concentration and temperature-sensitive diblock copolymers for doxorubicin delivery.
Biomaterials, 30(23): 3961-70. [Abstract] [Full-text]
- Group B streptococcus and early-onset sepsis in the era of maternal prophylaxis.
Pediatr Clin North Am, 56(3): 689-708, Table of Contents. [Abstract] [Full-text]
- Metabolic disorders induced by highly active antiretroviral therapy and their relationship with vascular remodeling of the brachial artery in a population of HIV-infected patients.
Metabolism, 58(7): 927-33. [Abstract] [Full-text]
- High frequency of antiretroviral drug resistance among HIV-infected adults receiving first-line highly active antiretroviral therapy in N'Djamena, Chad.
Clin Infect Dis, 49(1): 155-9. [Abstract] [Full-text]
- Improved survival in patients with breast rhabdoid tumors with multi-agent adjuvant chemotherapy combined with irradiation.
Cancer Chemother Pharmacol, 64(3): 623-7. [Abstract] [Full-text]
- Phase II study of paclitaxel combined with capecitabine as second-line treatment for advanced gastric carcinoma after failure of cisplatin-based regimens.
Cancer Chemother Pharmacol, 64(3): 549-55. [Abstract] [Full-text]
- Expression of ERCC1 and class III beta-tubulin in non-small cell lung cancer patients treated with a combination of cisplatin/docetaxel and concurrent thoracic irradiation.
Cancer Chemother Pharmacol, 64(3): 565-73. [Abstract] [Full-text]
- Ciprofloxacin sensitizes hormone-refractory prostate cancer cell lines to doxorubicin and docetaxel treatment on a schedule-dependent manner.
Cancer Chemother Pharmacol, 64(3): 445-54. [Abstract] [Full-text]
- A phase II trial evaluating capecitabine and irinotecan as second line treatment in patients with oesophago-gastric cancer who have progressed on, or within 3 months of platinum-based chemotherapy.
Cancer Chemother Pharmacol, 64(3): 455-62. [Abstract] [Full-text]
- Synergistic anti-tumor efficacy of lovastatin and protein kinase C-beta inhibitor in hepatocellular carcinoma.
Cancer Chemother Pharmacol, 64(3): 497-507. [Abstract] [Full-text]
- Indomethacin-loaded nanocapsules treatment reduces in vivo glioblastoma growth in a rat glioma model.
Cancer Lett, 281(1): 53-63. [Abstract] [Full-text]
- Molecular targeted treatment and radiation therapy for rectal cancer.
Strahlenther Onkol, 185(6): 371-8. [Abstract] [Full-text]
- Pooled analysis of individual patient-level data from all randomized, double-blind, placebo-controlled trials of darbepoetin alfa in the treatment of patients with chemotherapy-induced anemia.
J Clin Oncol, 27(17): 2838-47. [Abstract] [Full-text]
- Phase III noninferiority trial comparing irinotecan with oxaliplatin, fluorouracil, and leucovorin in patients with advanced colorectal carcinoma previously treated with fluorouracil: N9841.
J Clin Oncol, 27(17): 2848-54. [Abstract] [Full-text]
- Results of a phase III, randomized, placebo-controlled study of sorafenib in combination with carboplatin and paclitaxel as second-line treatment in patients with unresectable stage III or stage IV melanoma.
J Clin Oncol, 27(17): 2823-30. [Abstract] [Full-text]
- Phase I study of ixabepilone, mitoxantrone, and prednisone in patients with metastatic castration-resistant prostate cancer previously treated with docetaxel-based therapy: a study of the department of defense prostate cancer clinical trials consortium.
J Clin Oncol, 27(17): 2772-8. [Abstract] [Full-text]
- Pharmacogenetic analyses of a phase III trial in metastatic gastroesophageal adenocarcinoma with fluorouracil and leucovorin plus either oxaliplatin or cisplatin: a study of the arbeitsgemeinschaft internistische onkologie.
J Clin Oncol, 27(17): 2863-73. [Abstract] [Full-text]
- Feasibility trial of partial breast irradiation with concurrent dose-dense doxorubicin and cyclophosphamide in early-stage breast cancer.
J Clin Oncol, 27(17): 2816-22. [Abstract] [Full-text]
- Efficacy and safety of ritonavir-boosted dual protease inhibitor therapy in antiretroviral-naive HIV-1-infected patients: the 2IP ANRS 127 study.
J Antimicrob Chemother, 64(1): 118-25. [Abstract] [Full-text]
- A randomized trial of two-drug versus three-drug tenofovir-containing maintenance regimens in virologically controlled HIV-1 patients.
J Antimicrob Chemother, 64(1): 126-34. [Abstract] [Full-text]
- Effects of intranasally applied dopamine on behavioral asymmetries in rats with unilateral 6-hydroxydopamine lesions of the nigro-striatal tract.
Neuroscience, 162(1): 174-83. [Abstract] [Full-text]
- Dynamics of magnetic lipoplexes studied by single particle tracking in living cells.
J Control Release, 137(2): 136-45. [Abstract] [Full-text]
- A fast screening strategy for characterizing peptide delivery by transdermal iontophoresis.
J Control Release, 137(2): 123-9. [Abstract] [Full-text]
- Design and evaluation of novel fast forming pilocarpine-loaded ocular hydrogels for sustained pharmacological response.
J Control Release, 137(2): 152-9. [Abstract] [Full-text]
- Extracellular matrix binding mixed micelles for drug delivery applications.
J Control Release, 137(2): 146-51. [Abstract] [Full-text]
- Surface engineering of microparticles by novel protein transfer for targeted antigen/drug delivery.
J Control Release, 137(2): 90-7. [Abstract] [Full-text]
- Prehospital intraosseus access with the bone injection gun by a helicopter-transported emergency medical team.
J Trauma, 66(6): 1739-41. [Abstract] [Full-text]
- Anti-inflammatory resuscitation improves survival in hemorrhage with trauma.
J Trauma, 66(6): 1632-9; discussion 1639-40. [Abstract] [Full-text]
- Bevacizumab combined with gemcitabine and capecitabine for advanced pancreatic cancer: a phase II study.
Br J Cancer, 100(12): 1842-5. [Abstract] [Full-text]
- Evaluation of sub-acute changes in cardiac function after cisplatin-based combination chemotherapy for testicular cancer.
Br J Cancer, 100(12): 1861-6. [Abstract] [Full-text]
- Treatment intensification does not reduce residual HIV-1 viremia in patients on highly active antiretroviral therapy.
Proc Natl Acad Sci U S A, 106(23): 9403-8. [Abstract] [Full-text]
- Haematodermic CD4+CD56+ neoplasm: complete remission after methotrexate-asparaginase treatment.
Clin Exp Dermatol, 34(5): e43-5. [Abstract] [Full-text]
- Polyelectrolyte nanoparticles based on water-soluble chitosan-poly(L-aspartic acid)-polyethylene glycol for controlled protein release.
Carbohydr Res, 344(10): 1197-204. [Abstract] [Full-text]
- Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer.
Science, 324(5933): 1457-61. [Abstract] [Full-text]
- Differential efficacy of bortezomib plus chemotherapy within molecular subtypes of diffuse large B-cell lymphoma.
Blood, 113(24): 6069-76. [Abstract] [Full-text]
- Methotrexate/6-mercaptopurine maintenance therapy influences the risk of a second malignant neoplasm after childhood acute lymphoblastic leukemia: results from the NOPHO ALL-92 study.
Blood, 113(24): 6077-84. [Abstract] [Full-text]
- Polymeric nanomedicine for cancer MR imaging and drug delivery.
Chem Commun (Camb). [Abstract] [Full-text]
- Management of limb ischaemia in the neonate and infant.
Eur J Vasc Endovasc Surg, 38(1): 61-5. [Abstract] [Full-text]
- Bcl-2 family proteins contribute to apoptotic resistance in lung cancer multicellular spheroids.
Am J Respir Cell Mol Biol, 41(1): 14-23. [Abstract] [Full-text]
- Reproductive history, hormonal factors and the incidence of hip and knee replacement for osteoarthritis in middle-aged women.
Ann Rheum Dis, 68(7): 1165-70. [Abstract] [Full-text]
- Preliminary in vitro evaluation of an adjunctive therapy for extremity wound infection reduction: rapidly resorbing local antibiotic delivery.
J Orthop Res, 27(7): 903-8. [Abstract] [Full-text]
- Nanoencapsulation increases quinine antimalarial efficacy against Plasmodium berghei in vivo.
Int J Antimicrob Agents, 34(2): 156-61. [Abstract] [Full-text]
- Effects of physicochemical properties of salting-out layer components on drug release.
Int J Pharm, 376(1): 13-21. [Abstract] [Full-text]
- Evaluation of the mechanical properties and drug release of cross-linked Eudragit films containing metronidazole.
Int J Pharm, 376(1): 1-6. [Abstract] [Full-text]
- Heparin-functionalized chitosan-alginate scaffolds for controlled release of growth factor.
Int J Pharm, 376(1): 69-75. [Abstract] [Full-text]
- Comparison of subjective, pharmacokinetic, and physiological effects of marijuana smoked as joints and blunts.
Drug Alcohol Depend, 103(3): 107-13. [Abstract] [Full-text]
- Route of administration influences substitution patterns in rats trained to discriminate methadone vs. vehicle.
Drug Alcohol Depend, 103(3): 124-30. [Abstract] [Full-text]
- Optimization of epirubicin nanoparticles using experimental design for enhanced intravesical drug delivery.
Int J Pharm, 376(1): 195-203. [Abstract] [Full-text]
- Chemical stability and phase distribution of all-trans-retinol in nanoparticle-coated emulsions.
Int J Pharm, 376(1): 186-94. [Abstract] [Full-text]
- Facile fabrication of well-defined hydrogel beads with magnetic nanocomposite shells.
Int J Pharm, 376(1): 92-8. [Abstract] [Full-text]
- Chitosan solutions and particles: evaluation of their permeation enhancing potential on MDCK cells used as blood brain barrier model.
Int J Pharm, 376(1): 104-9. [Abstract] [Full-text]
- Hyperbranched polysiloxysilane nanoparticles: surface charge control of nonviral gene delivery vectors and nanoprobes.
Int J Pharm, 376(1): 141-52. [Abstract] [Full-text]
- A new micro/nanoencapsulated porphyrin formulation for PDT treatment.
Int J Pharm, 376(1): 76-83. [Abstract] [Full-text]
- Micronization of silybin by the emulsion solvent diffusion method.
Int J Pharm, 376(1): 116-22. [Abstract] [Full-text]
- Paclitaxel-loaded Pluronic P123/F127 mixed polymeric micelles: formulation, optimization and in vitro characterization.
Int J Pharm, 376(1): 176-85. [Abstract] [Full-text]
- Nanoparticle formation from probucol/PVP/sodium alkyl sulfate co-ground mixture.
Int J Pharm, 376(1): 169-75. [Abstract] [Full-text]
- Synthesis, characterization, drug-loading capacity and safety of novel octyl modified serum albumin micelles.
Int J Pharm, 376(1): 161-8. [Abstract] [Full-text]
- Development of PMMA membranes functionalized with hydroxypropyl-beta-cyclodextrins for controlled drug delivery using a supercritical CO(2)-assisted technology.
Int J Pharm, 376(1): 110-5. [Abstract] [Full-text]
- pH-sensitive properties of surface charge-switched multifunctional polymeric micelle.
Int J Pharm, 376(1): 134-40. [Abstract] [Full-text]
- Approach to design push-pull osmotic pumps.
Int J Pharm, 376(1): 56-62. [Abstract] [Full-text]
- The complexation between novel comb shaped amphiphilic polyallylamine and insulin: towards oral insulin delivery.
Int J Pharm, 376(1): 46-55. [Abstract] [Full-text]
- Synthesis of cationic derivatives of Quil A and the preparation of cationic immune-stimulating complexes (ISCOMs).
Int J Pharm, 376(1): 123-33. [Abstract] [Full-text]
- Evaluation of antibiotic prophylaxis in reducing postoperative infection after mandibular third molar extraction in young patients.
J Oral Maxillofac Surg, 67(7): 1467-72. [Abstract] [Full-text]
- Current issues in prevention of mother-to-child transmission of HIV-1.
Curr Opin HIV AIDS, 4(4): 319-24. [Abstract] [Full-text]
- The encapsulation and intracellular delivery of trehalose using a thermally responsive nanocapsule.
Nanotechnology, 20(27): 275101. [Abstract] [Full-text]
- A mesoporous silica nanosphere-based drug delivery system using an electrically conducting polymer.
Nanotechnology, 20(27): 275102. [Abstract] [Full-text]
- Evaluation of universal antenatal screening for group B streptococcus.
N Engl J Med, 360(25): 2626-36. [Abstract] [Full-text]
- Intravascular flow patterns in transforaminal epidural injections: a comparative study of the cervical and lumbar vertebral segments.
Anesth Analg, 109(1): 233-9. [Abstract] [Full-text]
- Nonresponse to pre-operative chemotherapy does not preclude long-term survival after liver resection in patients with colorectal liver metastases.
Surgery, 146(1): 52-9. [Abstract] [Full-text]
- Association of Thrombolysis in Myocardial Infarction Myocardial Perfusion Grade with cardiovascular magnetic resonance measures of infarct architecture after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction.
Am Heart J, 158(1): 84-91. [Abstract] [Full-text]
- Potential reductions in United States coronary heart disease mortality by treating more patients.
Am J Cardiol, 103(12): 1703-9. [Abstract] [Full-text]
- Multicenter phase II trial of neoadjuvant pemetrexed plus cisplatin followed by extrapleural pneumonectomy and radiation for malignant pleural mesothelioma.
J Clin Oncol, 27(18): 3007-13. [Abstract] [Full-text]
- Phase II study of tirapazamine, cisplatin, and etoposide and concurrent thoracic radiotherapy for limited-stage small-cell lung cancer: SWOG 0222.
J Clin Oncol, 27(18): 3014-9. [Abstract] [Full-text]
- High frequency of clinically significant mutations after first-line generic highly active antiretroviral therapy failure: implications for second-line options in resource-limited settings.
Clin Infect Dis, 49(2): 306-9. [Abstract] [Full-text]
- Chemotherapy treatment in pediatric patients with acute myeloid leukemia receiving antimicrobial prophylaxis leads to a relative increase of colonization with potentially pathogenic bacteria in the gut.
Clin Infect Dis, 49(2): 262-70. [Abstract] [Full-text]
- In vitro macrophage uptake and in vivo biodistribution of long-circulation nanoparticles with poly(ethylene-glycol)-modified PLA (BAB type) triblock copolymer.
Colloids Surf B Biointerfaces, 72(2): 303-11. [Abstract] [Full-text]
- Design and influence of gamma-irradiation on the biopharmaceutical properties of nanoparticles containing an antigenic complex from Brucella ovis.
Eur J Pharm Sci, 37(5): 563-72. [Abstract] [Full-text]
- Influence of structural variations on drug release from lipid/polyethylene glycol matrices.
Eur J Pharm Sci, 37(5): 555-62. [Abstract] [Full-text]
- The GD2-specific 14G2a monoclonal antibody induces apoptosis and enhances cytotoxicity of chemotherapeutic drugs in IMR-32 human neuroblastoma cells.
Cancer Lett, 281(2): 171-82. [Abstract] [Full-text]
- Complement upregulation in photodynamic therapy-treated tumors: Role of Toll-like receptor pathway and NFkappaB.
Cancer Lett, 281(2): 232-8. [Abstract] [Full-text]
- Comparison of primary percutaneous coronary intervention and fibrinolytic therapy in ST-segment-elevation myocardial infarction: bayesian hierarchical meta-analyses of randomized controlled trials and observational studies.
Circulation, 119(24): 3101-9. [Abstract] [Full-text]
- Endovascular repair of infrarenal abdominal aortic aneurysm associated with a horseshoe kidney and graft thrombosis in early follow-up.
Acta Radiol, 50(6): 624-8. [Abstract] [Full-text]
- Statins for all: the new premed?
Br J Anaesth, 103(1): 99-107. [Abstract] [Full-text]
- What are next generation innovative therapeutic targets? Clues from genetic, structural, physicochemical, and systems profiles of successful targets.
J Pharmacol Exp Ther, 330(1): 304-15. [Abstract] [Full-text]
- A phase II study of preradiotherapy chemotherapy followed by hyperfractionated radiotherapy for newly diagnosed high-risk medulloblastoma/primitive neuroectodermal tumor: a report from the Children's Oncology Group (CCG 9931).
Int J Radiat Oncol Biol Phys, 74(4): 1006-11. [Abstract] [Full-text]
- Factors associated with severe acute esophagitis from hyperfractionated radiotherapy with concurrent chemotherapy for limited-stage small-cell lung cancer.
Int J Radiat Oncol Biol Phys, 74(4): 1108-13. [Abstract] [Full-text]
- Pattern electroretinographic results after photodynamic therapy alone and photodynamic therapy in combination with intravitreal bevacizumab for choroidal neovascularization in age-related macular degeneration.
Doc Ophthalmol, 119(1): 37-42. [Abstract] [Full-text]
- Transitions of multifocal electroretinography following combined intravitreal bevacizumab and photodynamic therapy for polypoidal choroidal vasculopathy.
Doc Ophthalmol, 119(1): 29-36. [Abstract] [Full-text]
- A drug-eluting contact lens.
Invest Ophthalmol Vis Sci, 50(7): 3346-52. [Abstract] [Full-text]
- Suppression of shivering during hypothermia using a novel drug combination in healthy volunteers.
Anesthesiology, 111(1): 110-5. [Abstract] [Full-text]
- Treating childhood acute lymphoblastic leukemia without cranial irradiation.
N Engl J Med, 360(26): 2730-41. [Abstract] [Full-text]
- Routine early angioplasty after fibrinolysis for acute myocardial infarction.
N Engl J Med, 360(26): 2705-18. [Abstract] [Full-text]
- Retrospective comparison of bortezomib-containing regimens with vincristine-doxorubicin-dexamethasone (VAD) as induction treatment prior to autologous stem cell transplantation for multiple myeloma.
Jpn J Clin Oncol, 39(7): 449-55. [Abstract] [Full-text]
- Benefits and risks of postmenopausal hormone therapy when it is initiated soon after menopause.
Am J Epidemiol, 170(1): 12-23. [Abstract] [Full-text]
- Invited Commentary: Hormone therapy risks and benefits--The Women's Health Initiative findings and the postmenopausal estrogen timing hypothesis.
Am J Epidemiol, 170(1): 24-8. [Abstract] [Full-text]
- Phase II trial of concurrent chemoradiotherapy with S-1 plus cisplatin in patients with unresectable locally advanced squamous cell carcinoma of the head and neck: Japan Clinical Oncology Group Study (JCOG0706).
Jpn J Clin Oncol, 39(7): 460-3. [Abstract] [Full-text]
- Randomized controlled study comparing two doses of intravenous granisetron (1 and 3 mg) for acute chemotherapy-induced nausea and vomiting in cancer patients: a non-inferiority trial.
Jpn J Clin Oncol, 39(7): 443-8. [Abstract] [Full-text]
- Relapse with malignant transformation after chemotherapy for primary mediastinal seminoma: case report.
Jpn J Clin Oncol, 39(7): 456-9. [Abstract] [Full-text]
- NF-kappaB activation through the alternative pathway correlates with chemoresistance and poor survival in extranodal NK/T-cell lymphoma, nasal type.
Jpn J Clin Oncol, 39(7): 418-24. [Abstract] [Full-text]
- Risk factors for severe Dysphagia after concurrent chemoradiotherapy for head and neck cancers.
Jpn J Clin Oncol, 39(7): 413-7. [Abstract] [Full-text]
- The success of primary chemotherapy for group D heritable retinoblastoma.
Br J Ophthalmol, 93(7): 887-90. [Abstract] [Full-text]
- Pemetrexed combined with paclitaxel: a dose-finding study evaluating three schedules in solid tumors.
Invest New Drugs, 27(4): 356-65. [Abstract] [Full-text]
- Phase I trial of weekly cisplatin, irinotecan and paclitaxel in patients with advanced gastrointestinal cancer.
Invest New Drugs, 27(4): 366-73. [Abstract] [Full-text]
- Is transketolase like 1 a target for the treatment of differentiated thyroid carcinoma? A study on thyroid cancer cell lines.
Invest New Drugs, 27(4): 297-303. [Abstract] [Full-text]
- Virological monitoring and resistance to first-line highly active antiretroviral therapy in adults infected with HIV-1 treated under WHO guidelines: a systematic review and meta-analysis.
Lancet Infect Dis, 9(7): 409-17. [Abstract] [Full-text]
- Synergistic inhibition effect of tumor growth by using celecoxib in combination with oxaliplatin.
Cancer Invest, 27(6): 636-40. [Abstract] [Full-text]
- Curcumin sensitizes lung cancer cells to cisplatin-induced apoptosis through superoxide anion-mediated Bcl-2 degradation.
Cancer Invest, 27(6): 624-35. [Abstract] [Full-text]
- Unintended consequence of plant transformation: biolistic transformation caused transpositional activation of an endogenous retrotransposon Tos17 in rice ssp. japonica cv. Matsumae.
Plant Cell Rep, 28(7): 1043-51. [Abstract] [Full-text]
- Comparison of drug dosing recommendations based on measured GFR and kidney function estimating equations.
Am J Kidney Dis, 54(1): 33-42. [Abstract] [Full-text]
- Southwest Oncology Group Trial S9912: intraperitoneal cisplatin and paclitaxel plus intravenous paclitaxel and pegylated liposomal doxorubicin as primary chemotherapy of small-volume residual stage III ovarian cancer.
Gynecol Oncol, 114(2): 206-9. [Abstract] [Full-text]
- Phase 2 trial of two courses of cyclophosphamide and etoposide for relapsed high-risk osteosarcoma patients.
Cancer, 115(13): 2980-7. [Abstract] [Full-text]
- Racial and socioeconomic disparities in adjuvant chemotherapy for older women with lymph node-positive, operable breast cancer.
Cancer, 115(13): 2999-3008. [Abstract] [Full-text]
- The timing of normalization of CA-125 levels during primary chemotherapy is predictive of survival in patients with epithelial ovarian cancer.
Gynecol Oncol, 114(2): 242-5. [Abstract] [Full-text]
- Topotecan combined with carboplatin in recurrent epithelial ovarian cancer: results of a single-institutional phase II study.
Gynecol Oncol, 114(2): 210-4. [Abstract] [Full-text]
- Combined weekly carboplatin and paclitaxel as primary treatment of advanced epithelial ovarian carcinoma.
Gynecol Oncol, 114(2): 215-8. [Abstract] [Full-text]
- Tumor microRNA expression patterns associated with resistance to platinum based chemotherapy and survival in ovarian cancer patients.
Gynecol Oncol, 114(2): 253-9. [Abstract] [Full-text]
- IgE-mediated allergen gene vaccine platform targeting human antigen-presenting cells through the high-affinity IgE receptor.
J Allergy Clin Immunol, 124(1): 108-13. [Abstract] [Full-text]
- Locally advanced rectal cancer: MR imaging for restaging after neoadjuvant radiation therapy with concomitant chemotherapy. Part II. What are the criteria to predict involved lymph nodes?
Radiology, 252(1): 81-91. [Abstract] [Full-text]
- Locally advanced rectal cancer: MR imaging for restaging after neoadjuvant radiation therapy with concomitant chemotherapy. Part I. Are we able to predict tumor confined to the rectal wall?
Radiology, 252(1): 71-80. [Abstract] [Full-text]
- Phase 1 trial of temozolomide plus irinotecan plus O6-benzylguanine in adults with recurrent malignant glioma.
Cancer, 115(13): 2964-70. [Abstract] [Full-text]
- High-dose chemotherapy and autologous hematopoietic progenitor cell rescue in children with recurrent medulloblastoma and supratentorial primitive neuroectodermal tumors: the impact of prior radiotherapy on outcome.
Cancer, 115(13): 2956-63. [Abstract] [Full-text]
- Improving glucocorticoid replacement therapy using a novel modified-release hydrocortisone tablet: a pharmacokinetic study.
Eur J Endocrinol, 161(1): 119-30. [Abstract] [Full-text]
- Histologic and manometric studies on the esophagus following endoscopic sclerotherapy.
Dig Dis Sci, 54(8): 1713-9. [Abstract] [Full-text]
- Persistence of androgenic effects on the production of proinflammatory cytokines by circulating antigen-presenting cells after withdrawal of testosterone treatment in aging type 2 diabetic men with partial androgen deficiency.
Fertil Steril, 92(1): 311-9. [Abstract] [Full-text]
- Enhanced neuroactivation during verbal memory processing in postmenopausal women receiving short-term hormone therapy.
Fertil Steril, 92(1): 197-204. [Abstract] [Full-text]
- The relationship between genotypic sensitivity score and treatment outcomes in late stage HIV disease after supervised HAART.
J Med Virol, 81(8): 1323-35. [Abstract] [Full-text]
- Preparation and properties of hydroxycamptothecin-loaded nanoparticles made of amphiphilic copolymer and normal polymer.
J Colloid Interface Sci, 336(2): 808-13. [Abstract] [Full-text]
- An audit of prophylactic antibiotic use in laryngeal reconstruction surgery.
Int J Pediatr Otorhinolaryngol, 73(8): 1157-9. [Abstract] [Full-text]
- Preparation of an amphiphilic triblock copolymer with pH- and thermo-responsiveness and self-assembled micelles applied to drug release.
J Colloid Interface Sci, 336(2): 865-71. [Abstract] [Full-text]
- Phase II study of ASA404 (vadimezan, 5,6-dimethylxanthenone-4-acetic acid/DMXAA) 1800mg/m(2) combined with carboplatin and paclitaxel in previously untreated advanced non-small cell lung cancer.
Lung Cancer, 65(2): 192-7. [Abstract] [Full-text]
- Peripheral benzodiazepine receptor ligand-PLGA polymer conjugates potentially useful as delivery systems of apoptotic agents.
J Control Release, 137(3): 185-95. [Abstract] [Full-text]
- Tailor-made dissolution profiles by extruded matrices based on lipid polyethylene glycol mixtures.
J Control Release, 137(3): 211-6. [Abstract] [Full-text]
- A new class of inhibitors of peptide sorption and acylation in PLGA.
J Control Release, 137(3): 179-84. [Abstract] [Full-text]
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Lung Cancer, 65(2): 129-37. [Abstract] [Full-text]
- A multicenter randomized phase II study of the irinotecan/gemcitabine doublet versus irinotecan monotherapy in previously treated patients with extensive stage small-cell lung cancer.
Lung Cancer, 65(2): 187-91. [Abstract] [Full-text]
- Selective pulmonary artery perfusion for the treatment of primary lung cancer: Improved drug exposure of the lung.
Lung Cancer, 65(2): 208-13. [Abstract] [Full-text]
- UHMWPE carrying estradiol to treat the particle-induced osteolysis-Processing and characterizing.
J Biomed Mater Res A, 90(2): 496-505. [Abstract] [Full-text]
- pH-dependent self-assembling behavior of imidazole-containing polyaspartamide derivatives.
J Biomed Mater Res A, 90(2): 478-86. [Abstract] [Full-text]
- Controlled delivery of paclitaxel from stent coatings using novel styrene maleic anhydride copolymer formulations.
J Biomed Mater Res A, 90(2): 522-32. [Abstract] [Full-text]
- Better posttransplant outcome with fludarabine based conditioning in multitransfused fanconi anemia patients who underwent peripheral blood stem cell transplantation.
J Pediatr Hematol Oncol, 31(7): 512-5. [Abstract] [Full-text]
- 'Injecting' yeast.
Nat Methods, 6(7): 513-4. [Abstract] [Full-text]
- Improved overall survival with oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment in stage II or III colon cancer in the MOSAIC trial.
J Clin Oncol, 27(19): 3109-16. [Abstract] [Full-text]
- Randomized phase III trial comparing biweekly infusional fluorouracil/leucovorin alone or with irinotecan in the adjuvant treatment of stage III colon cancer: PETACC-3.
J Clin Oncol, 27(19): 3117-25. [Abstract] [Full-text]
- Phase III study by the Norwegian lung cancer study group: pemetrexed plus carboplatin compared with gemcitabine plus carboplatin as first-line chemotherapy in advanced non-small-cell lung cancer.
J Clin Oncol, 27(19): 3217-24. [Abstract] [Full-text]
- Genomic grade index is associated with response to chemotherapy in patients with breast cancer.
J Clin Oncol, 27(19): 3185-91. [Abstract] [Full-text]
- Relationship of blood pressure, antihypertensive therapy, and outcome in ischemic stroke treated with intravenous thrombolysis: retrospective analysis from Safe Implementation of Thrombolysis in Stroke-International Stroke Thrombolysis Register (SITS-ISTR).
Stroke, 40(7): 2442-9. [Abstract] [Full-text]
- Gender differences in acute ischemic stroke: etiology, stroke patterns and response to thrombolysis.
Stroke, 40(7): 2428-32. [Abstract] [Full-text]
- Blood volume measurement to guide fluid therapy after aneurysmal subarachnoid hemorrhage: a prospective controlled study.
Stroke, 40(7): 2575-7. [Abstract] [Full-text]
- Is it time to reassess the SITS-MOST criteria for thrombolysis?: A comparison of patients with and without SITS-MOST exclusion criteria.
Stroke, 40(7): 2568-71. [Abstract] [Full-text]
- Clinical-diffusion mismatch and benefit from thrombolysis 3 to 6 hours after acute stroke.
Stroke, 40(7): 2572-4. [Abstract] [Full-text]
- Facile fabrication method and characterization of hollow Ag/SiO2 double-shelled spheres.
Langmuir, 25(13): 7646-51. [Abstract] [Full-text]
- Carboxyl enriched monodisperse porous Fe3O4 nanoparticles with extraordinary sustained-release property.
Langmuir, 25(13): 7244-8. [Abstract] [Full-text]
- Mirena (Levonorgestrel intrauterine system): a successful novel drug delivery option in contraception.
Adv Drug Deliv Rev, 61(10): 808-12. [Abstract] [Full-text]
- Drug delivery for in vitro fertilization: rationale, current strategies and challenges.
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- Intelligent polymeric micelles from functional poly(ethylene glycol)-poly(amino acid) block copolymers.
Adv Drug Deliv Rev, 61(10): 768-84. [Abstract] [Full-text]
- Current challenges in clinical management of endometrial cancer.
Adv Drug Deliv Rev, 61(10): 883-9. [Abstract] [Full-text]
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